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美国人使用的处方药比以往任何时候都多. Consequently, they’re coping with more side effects, drug interactions, and costs, especially if they’re using multiple medications. 凯撒永久华盛顿健康利记官网所(利记官网)的科学家们正站在回答这些问题的前沿. 我们正在利记官网药物在现实环境中的有益和有害影响, 创新管理和监测药物使用的更好方法.
该利记官网所为监测药物安全的国家倡议作出贡献，并提供信息，帮助医生和患者权衡各种处方药的风险和益处.
利记官网药物使用和患者安全利记官网的资助者包括 Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, the Patient-Centered Outcomes Research Institute, and other sources. A few projects include:
刘国强，李国强，李国强，李国强，李国强，李国强，李国强. 对阿得拉的预期影响主观情绪和药物效果，而不考虑同时摄入咖啡因:一项随机对照试验. Psychopharmacology (Berl). 2023 Sep 23. doi: 10.1007/s00213-023-06467-8. Online ahead of print. PubMed
陈毅，Loucks AR, Sullivan SD, Pearson SD, Kent D，杨凯. 为商业健康计划设计基于价值的处方:糖尿病药物的模拟案例利记官网. Value Health. 2023 Feb 14:S1098-3015(23)00053-0. doi: 10.1016/j.jval.2023.02.004. [Epub ahead of print]. PubMed
Tchesnokova V, Larson L, Basova I, Sledneva Y, Choudhury D, Heng J, Solyanik T, Bonilla T, Pham S, Schartz E, Madziwa L, Holden E, Weissman S, Ralston J, Sokurenko E. 尽管抗生素处方减少，但耐氟喹诺酮类大肠杆菌肠道携带率增加. Res Sq. 2023 Jan 12;rs.3.rs-2426668. doi: 10.21203/rs.3.rs-2426668/v1. Preprint. PubMed
Chen C, Hennessy S, Brensinger CM, Bilker WB, Dublin S, Chung SP, Horn JR, Bogar KF, Leonard CE. 抗抑郁药-药物-药物相互作用与非故意创伤性损伤相关:筛选现实世界数据中的信号. Clin Transl Sci. 2022 Nov 22. doi: 10.1111/cts.13452 [Epub ahead of print] PubMed
Carrell DS, Gruber S, Floyd JS, Bann MA, Cushing-Haugen KL, Johnson RL, Graham V, Cronkite DJ, Hazlehurst BL, Felcher AH, Bejan CA, Kennedy A, Shinde M, Karami S, Ma Y, Stojanovic D, Zhao Y, Ball R, Nelson J. 使用自然语言处理和机器学习改进医疗产品安全监测中过敏反应的识别方法. Am J Epidemiol. 2022 Nov 4:kwac182. doi: 10.1093/aje/kwac182. [Epub ahead of print]. PubMed
 Sascha Dublin, MD, PhDSenior Investigator |
 Jessica Chubak, PhDSenior Investigator |
 Andrea J. Cook, PhDSenior Biostatistics Investigator |
 Rita Mangione-Smith, MD, MPHExecutive Director and Senior Investigator, 利记官网; Vice President for Research and Health Care Innovation, 利记官网 Washington |
 Jennifer C. Nelson, PhDDirector, Biostatistics; Senior Investigator |
 David E. Arterburn, MD, MPHSenior Investigator |
 Susan M. Shortreed, PhDSenior Biostatistics Investigator |
 Lisa A. Jackson, MD, MPHSenior Investigator |
 Karen Wernli, PhDSenior Investigator |
 Onchee Yu, MSPrincipal Collaborative Biostatistician |
 Rod L. Walker, MSSenior Collaborative Biostatistician |
 Robert D. Wellman, MSSenior Collaborative Biostatistician |
 Gaia Pocobelli, PhDSenior Collaborative Scientist |
 David S. Carrell, PhDAssociate Investigator |
 Laura Harrington, PhD, MPHAssistant Investigator |
 Jennifer F. Bobb, PhDAssociate Biostatistics Investigator |
 Weiwei Zhu, MSSenior Collaborative Biostatistician |
 Paige D. Wartko, PhD, MPHCollaborative Scientist |
 Maricela Cruz, PhDAssistant Biostatistics Investigator |
 Brian D. Williamson, PhDAssistant Biostatistics Investigator |
 Noorie Hyun, PhDAssistant Biostatistics Investigator |
 Laurel Hansell, MA, MPHCollaborative Scientist |
 Jess Mogk, MPHCollaborative Scientist |
 Annie Piccorelli, PhDSenior Collaborative Biostatistician |
Susan Heckbert, MD, PhD
University of Washington (UW) Department of Epidemiology; UW Cardiovascular Health Research Unit
David Siscovick, MD, MPH
UW Department of Medicine; UW Department of Epidemiology; UW Cardiovascular Health Research Unit
Leslie Spangler, PhD
Amgen
A team led by 利记官网's Kai Yeung, PharmD, PhD, 回顾了3种治疗方法的成本效益试验结果.
Dr. Sascha Dublin explains why sometimes not 服用药物可能是更安全、更健康的选择.
新的利记官网检查了提供者的笔记，以了解患者的大麻使用和健康状况.
利记官网人员需要更大的数据集才能找到有意义的结果. Sascha Dublin and colleagues write in Pediatrics.
New funding will establish an innovation center, 由哈佛朝圣者与利记官网和其他机构合作领导.
利记官网人员发现，处方中枢神经系统活性药物与老年痴呆症患者摔倒风险增加之间存在关系.
Land Acknowledgment
我们的西雅图办公室坐落在杜瓦米什人占领的土地上，靠近海岸萨利什人的共享水域, who have been here thousands of years and remain. Learn about practicing land acknowledgment.
